agalsidase beta (Fabrazyme, Replagal)

Introduction

Tradename: Fabrazyme (FDA approved 2003)

Indications

• Fabry's disease

Mechanism of action

• recombinant human alpha-galactosidase A

More general terms

• alpha-galactosidase A (ceramide trihexosidase, melibiase, GLA)
• recombinant protein; chimer
• metabolic agent (metabolic modifier)

Additional terms

• pegunigalsidase alfa-iwxj (Elfabrio)