genome editing
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Indications
- basic medical research
- clinical applications in somatic cells with effects limited to treated individuals
- clinical applications in germline cells
Methods
- RNA-guided CRISPR-Cas9 genome editing system is more efficient, less costly, & easier to use than earlier protein-guided technologies such as zinc finger nucleases & TALENs.[1]
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Additional terms
References
- ↑ 1.0 1.1 Hynes RO, Coller BS, Porteus M Toward Responsible Human Genome Editing. JAMA. Published online April 10, 2017. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28395003 <Internet> http://jamanetwork.com/journals/jama/fullarticle/2618432