P504S+p63+cytokeratin 903 Ag in tissue
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Indications
- evaluation of prostate cancer
* occasional benign glands, high-grade prostatic intraepithelial neoplasia, atypical adenomatous hyperplasia, & urothelial carcinoma may express P504S[2]
* 504S is best used only in conjunction with strict light microscopy correlation & preferably with high molecular weight cytokeratin immunostaining[2]
More general terms
Additional terms
- cytokeratin, epithelial keratins or soft alpha-keratins
- p63 protein; p53 homolog p63; tumor protein p73-like; p73L; TP63; p51; p40; keratinocyte transcription factor KET; chronic ulcerative stomatitis protein (CUSP, TP73L, KET, p63, P73H)
- prostate cancer
References
- ↑ Jiang Z, Woda BA, Rock KL et al P504S: a new molecular marker for the detection of prostate carcinoma. Am J Surg Pathol. 2001 Nov;25(11):1397-404. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11684956
- ↑ 2.0 2.1 2.2 Beach R, Gown AM, De Peralta-Venturina MN et al P504S immunohistochemical detection in 405 prostatic specimens including 376 18-gauge needle biopsies. Am J Surg Pathol. 2002 Dec;26(12):1588-96. PMID: https://www.ncbi.nlm.nih.gov/pubmed/12459625