drug interaction(s) of gliptins with sulfonylureas
Jump to navigation
Jump to search
Drug interactions
- combination of gliptin with sulfonylurea
- increases risk for hypoglycemia[1]
- absolute risk 12% vs 7% for sulfonylurea alone[1]
- decreases risk for hypoglycemia (RR = 0.86)[2]
- increases risk for hypoglycemia[1]
More general terms
References
- ↑ 1.0 1.1 1.2 Salvo F et al Addition of dipeptidyl peptidase-4 inhibitors to sulphonylureas and risk of hypoglycaemia: systematic review and meta-analysis. BMJ 2016;353:i2231 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/27142267 Free full text <Internet> http://www.bmj.com/content/353/bmj.i2231
- ↑ 2.0 2.1 Hippisley-Cox J, Coupland C Diabetes treatments and risk of amputation, blindness, severe kidney failure, hyperglycaemia, and hypoglycaemia: open cohort study in primary care. BMJ 2016;352:i1450 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/27029547 <Internet> http://www.bmj.com/content/352/bmj.i1450
Montori VM Selecting the right drug treatment for adults with type 2 diabetes. BMJ 2016;352:i1663 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/27029501 <Internet> http://www.bmj.com/content/352/bmj.i1663