immunoglobulin heavy diversity 1-1 (IGHD1-1)

Function

• D region of the variable domain of immunoglobulin heavy chains
• variable domains are assembled by aprocess called V-(D)-J rearrangement & can then be subjected to somatic hypermutations which, after exposure to antigen & selection, allow affinity maturation for a particular antigen

Compartment

secreted

Polymorphism

• several alleles

More general terms

• immunoglobulin heavy chain

Database

• UniProt: http://www.uniprot.org/uniprot/P0DOY5.html