Humanin-like 11; HN11; MT-RNR2-like protein 11 (MTRNR2L11)

Function

• biologically active peptide
• plays a role as a neuroprotective & antiapoptotic factor

Structure

• belongs to the humanin family

Compartment

• secreted
• cytoplasm

Genetics

• product of a mitochondrial gene, MT-RNR2
• mechanisms allowing production & the secretion of humanin from the mitochondrial gene remaining unclear
• it is possible that the physiologically active humanin peptide is encoded by one of the related genes present in the nuclear genome

More general terms

• Humanin-like protein

Database

• UniProt: http://www.uniprot.org/uniprot/S4R3Y5.html