teixobactin
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Introduction
Newly discovered. experimental drug.
Epidemiology
- extracted from bacteria living in dirt
Antimicrobial activity
Gram positive bacteria, including
Mechanism of action
- binds to lipid II, precursor of peptidoglycan
- unlike vancomysin, binds modified forms of lipid II
Comparative biology
- effective in mice
Notes
- properties of teixobactin may suggest path towards developing antibiotics likley to avoid development of resistance[1]
More general terms
References
- ↑ 1.0 1.1 Ling L. Schneider T, Peoples AJ et al A new antibiotic kills pathogens without detectable resistance. Nature. Jan 7, 2015 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25561178 <Internet> http://www.nature.com/nature/journal/vaop/ncurrent/pdf/nature14098.pdf