histone antibody in serum

Indications

• present in drug-induced lupus
• not as frequent in idiopathic systemic lupus erythematosus

Storage

store at -20 C

Clinical significance

• 95% sensitivity for drug-induced lupus
• poor specificity

Methods

solid phase EIA

Specimen

serum

Interferences

• no chemical interferences or in vivo effects known

More general terms

• histone antibody in body fluid

More specific terms

• anti-histone H2a+H2b antibody in serum
• histone antibody in serum qualitative
• histone antibody in serum quantitative
• histone IgG in serum

Additional terms

• anti-histone antibody
• drug-induced lupus erythematosus