MPL gene mutation

Clinical significance

• defects in MPL are a cause of
  • congenital amegakaryocytic thrombocytopenia
  • essential thrombocythemia
  • myelofibrosis

More general terms

• gene mutation testing; gene mutation analysis

Additional terms

• thrombopoietin receptor; TPO-R; myeloproliferative leukemia protein; C-mpl; CD110 (MPL, TPOR)