mitochondrial Ca+2 uniporter regulator 1; coiled-coil domain-containing protein 90A, mitochondrial (MCUR1 C6orf79, CCDC90A)

Function

• key regulator of mitochondrial Ca+2 uniporter (MCU)
• required for Ca+2 entry into mitochondrion
• role in uniporter-mediated Ca+2 uptake, possibly via a direct interaction with MCU
• interacts with MCU

Structure

belongs to the CCDC90 family

Compartment

• mitochondrial inner membrane; multi-pass membrane protein

Alternative splicing

named isoforms=2

Expression

ubiquitously expressed

More general terms

• mitochondrial membrane protein
• transmembrane 2 protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=63933
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:63933
• UniProt: http://www.uniprot.org/uniprot/Q96AQ8.html