Bitot's spot

^[1]^[2]^[3]

Etiology

buildup of keratin superficially in the conjunctiva
conjunctival xerophthalmia
metaplasia of the conjunctival epithelium
tangles of keratin admixed with gas-forming bacteria (Corynebacterium xerosis), giving the lesion its typical foamy appearance

dry, superficial triangular scaly gray patch with a foamy appearance on the conjunctiva^[2]

* images^[2]^[3]

↑ Wikipedia: Bitot's spots http://en.wikipedia.org/wiki/Bitot's_spots
↑ ^2.0 ^2.1 ^2.2 Ferrari G, Vigano M (image) Bitot's Spot in Vitamin A Deficiency N Engl J Med 2013; 368:e29. May 30, 2013 PMID: https://www.ncbi.nlm.nih.gov/pubmed/23718174 DOI: 10.1056/NEJMicm1205309 [Indexed for MEDLINE] Free full text http://www.nejm.org/doi/full/10.1056/NEJMicm1205309
↑ ^3.0 ^3.1 Ram J, Jinagal J (images) Bitot's Spots. N Engl J Med 2018; 379:869. Aug 30, 2018 PMID: https://www.ncbi.nlm.nih.gov/pubmed/30157394 https://www.nejm.org/doi/full/10.1056/NEJMicm1715354