number needed to harm (NNH)

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Introduction

1/absolute risk increase.

For example, if risk with treatment is 20% vs 5% for placebo, the absolute risk increase is 0.20-0.05 = 0.15.

Thus, the number need to harm is 1/0.15 = 6.667 ~ 7

The number of patients needed to treat for a single patient to be harmed.

More general terms

Additional terms

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 16, 17. American College of Physicians, Philadelphia 2012, 2015
  2. The NNT: Quick summaries of evidence-based medicine. http://www.thennt.com/