limb pain

^[1]^[2]

Management

acetaminophen noninferior to diclofenac alone or to diclofenac plus acetaminophen in reducing acute minor musculoskeletal pain^[1]
ibuprofen & opioids similarly effective for short-term relief of acute extremity pain when combined with acetaminophen^[2]

↑ ^1.0 ^1.1 Ridderikhof ML, Lirk P, Goddijn H et al. Acetaminophen or nonsteroidal anti-inflammatory drugs in acute musculoskeletal trauma: A multicenter, double-blind, randomized, clinical trial. Ann Emerg Med 2017 Oct 13 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29033294 <Internet> http://www.annemergmed.com/article/S0196-0644(17)31506-8/fulltext
↑ ^2.0 ^2.1 Chang AK, Bijur PE, Esses D et al Effect of a Single Dose of Oral Opioid and Nonopioid Analgesics on Acute Extremity Pain in the Emergency Department. A Randomized Clinical Trial. JAMA. 2017;318(17):1661-1667 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29114833 https://jamanetwork.com/journals/jama/article-abstract/2661581
Kyriacou DN Opioid vs Nonopioid Acute Pain Management in the Emergency Department. JAMA. 2017;318(17):1655-1656 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29114813 https://jamanetwork.com/journals/jama/article-abstract/2661559