doxylamine/pyridoxine (Diclegis, Bendectin)

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Indications

Dosage

tablets must be taken on an empty stomach

Adverse effects

Notes

  • Bendectin was voluntarily pulled from the market in 1983 due to concerns about birth defects
    • those concerns later proved to be unfounded

More general terms

Components

References

  1. FDA News Release: April 8, 2013 FDA approves Diclegis for pregnant women experiencing nausea and vomiting. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm347087.htm
  2. 2.0 2.1 Persaud N, Meaney C, El-Emam K, Moineddin R, Thorpe K. Doxylamine-pyridoxine for nausea and vomiting of pregnancy randomized placebo controlled trial: Prespecified analyses and reanalysis. PLOS One. January 17, 2018 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29342163 Free full text <Internet> http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0189978