antimicrobial photodynamic therapy

^[1]

Procedure

uses a photosensitizing drug & visible light has been used to kill bacteria, viruses, & fungi
most photosensitizers show photodynamic activity against Gram-positive organisms
for Gram-negative bacteria, cationic photosensitizers are needed
- phenothiazinium derivatives are cationic photosensitizers that absorb light in the 630-680 nm range
ultraviolet radiation with germicidal lamps (ultraviolet C spectrum) has also been used to treat chronic leg ulcers

↑ Morley S et al. Phase IIa randomised, placebo-controlled study of antimicrobial photodynamic therapy in bacterially colonised, chronic leg ulcers and diabetic foot ulcers: A new approach to antimicrobial therapy. Br J Dermatol 2012 Oct 15; PMID: https://www.ncbi.nlm.nih.gov/pubmed/23066973