actin-related protein 3C; actin-related protein 11 (ACTR3C, ARP11)

Function

• may play a role in the suppression of metastatic potential in lung adenoma carcinoma cells

Structure

belongs to the actin family

Alternative splicing

named isoforms=2

Expression

• expressed in kidney, stomach, spleen, bone marrow, uterus, testis, placenta, skeletal muscle, mammary gland, lung, fetal liver, & fetal kidney
• not detected in small intestine, brain, & thymus

Pathology

• expressed in low-metastatic lung adenocarcinoma cells but not in high-metastatic ones

More general terms

• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=653857
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6538
• UniProt: http://www.uniprot.org/uniprot/Q9C0K3.html