sulfotransferase 1C4; ST1C4; sulfotransferase 1C2; SULT1C#2 (SULT1C4, SULT1C2)

Function

• catalyzes sulfate conjugation of many drugs, xenobiotics, & neurotransmitters
• may be involved in activation of carcinogenic hydroxylamines
• shows activity towards p-nitrophenol & N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF)

Structure

belongs to the sulfotransferase 1 family

Compartment

cytoplasm

Expression

• expressed at high levels in fetal lung & kidney
• expressed at low levels in fetal heart, adult kidney, ovary & spinal cord

More general terms

• sulfotransferase 1C

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=27233
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:27233
• OMIM: https://mirror.omim.org/entry/608357
• UniProt: http://www.uniprot.org/uniprot/O75897.html