endogenous Borna-like N element-1; EBLN-1
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Function
- may act as a RNA-binding protein
- highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA & oligomerizes (putative)
Expression
- expression detected by RT-PCR in a few cell lines, including OL, 293T & MOLT4
- not observed in HeLa cells
Notes
- Bornavirus is a non-retroviral RNA virus that does not generate DNA forms during viral replication
- therefore, integration of EBLN-1 must have occurred through a mechanism relying on an endogenous reverse transcriptase activity