intractable childhood epilepsy with generalized tonic-clonic seizures (ICEGTC)

Genetics

• associated with defects in SCN1A

Clinical manifestations

• generalized tonic-clonic seizures beginning usually in infancy & induced by fever
• seizures are associated with subsequent mental decline & ataxia or hypotonia
• ICEGTC is similar to SMEI, except for the absence of myoclonic seizures

More general terms

• epilepsy

Database

• OMIM: https://mirror.omim.org/entry/607208