ribose-5-phosphate isomerase; phosphoriboisomerase (RPIA RPI)

Function

• carbohydrate degradation; pentose phosphate pathway;
• D- ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1

D-ribose 5-phosphate = D-ribulose 5-phosphate

Structure

• belongs to the ribose 5-phosphate isomerase family

Pathology

• defects in RPIA are the cause of ribose-5-phosphate isomerase deficiency

Laboratory

• ribose-5-phosphate isomerase in fibroblasts
• ribose-5-phosphate isomerase in lymphoblasts

More general terms

• isomerase

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=22934
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:22934
• OMIM: https://mirror.omim.org/entry/180430
• OMIM: https://mirror.omim.org/entry/608611
• UniProt: http://www.uniprot.org/uniprot/P49247.html