endothelial cell-specific molecule 2 (ECSM2, ECSCR)

Function

• regulates endothelial chemotaxis & tube formation
• role in angiogenesis via modulation of the actin cytoskeleton
• interacts with FLNA

Structure

• may be heavily O-glycosylated
• belongs to the ECSM2 family

Compartment

cell membrane

Expression

endothelial-specific

More general terms

• membrane protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6417
• UniProt: http://www.uniprot.org/uniprot/Q19T08.html