dibucaine number

Indications

• pseudocholinesterase deficiency
• assessment of succinylcholine risk associated with surgery

Procedure

• the % of butyrylcholinesterase inhibited by dibucaine
• the patient's plasma is incubated with butyrylthiocholine along with the indicator 5,5'-dithiobis-(2-nitrobenzoic acid), which produce a colored product
• the dibucaine fluoride number is determined by repeating this assay in the presence of standard aliquots of dibucaine

Additional terms

• cholinesterase in serum/plasma
• dibucaine