catechol O-methyltransferase 2 (COMT2)

Function

• catalyzes the O-methylation, & thus inactivation, of catecholamine neurotransmitters & catechol hormones (putative)

Structure

• belongs to the methyltransferase superfamily
• catechol-O-methyltransferase family

Pathology

• defects in COMT2 are a cause of non-syndromic recessive deafness

More general terms

• O-methyl transferase

Database

• UniProt: http://www.uniprot.org/uniprot/Q8WZ04.html