Henderson-Hasselbalch equation

^[1]^[2]

Introduction

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pH = pKa + log ([HCO3-]/[H2CO3])

pH = 6.1 + log ([HCO3-]/[H2CO3])

pH = 61 + log ([HCO3-]/(0.03 x pCO2))

H+ (nmol/L) =  24 x pCO2 (mm Hg) / [HCO3-] (mmol/L)

Normal acid-base values:

    pCO2 = 38-42 mm Hg
 [HCO3-] = 24-28 mmol/L
    [H+] = 40 mmol/L

    pCO2 = 38-42 mm Hg
 [HCO3-] = 24-28 mmol/L
    [H+] = 40 mmol/L

↑ Medical Knowledge Self Assessment Program (MKSAP) 11, 14 American College of Physicians, Philadelphia 1998, 2006
↑ Clinical Diagnosis & Management by Laboratory Methods, 19th edition, J.B. Henry (ed), W.B. Saunders Co., Philadelphia, PA. 1996, pg 85,150,152