solute carrier family 48 member 1; heme transporter HRG1; heme-responsive gene 1 protein homolog; HRG-1; hHRG-1 (HRG1, SLC48A1)

Function

• heme transporter
• regulates intracellular heme availability through the endosomal or lysosomal compartment

Structure

belongs to the HRG family

Compartment

• endosome membrane
• lysosomal membrane

Alternative splicing

named isoforms=2

Expression

• highly expressed in the brain, kidney, heart & skeletal muscle
• moderately expressed in the liver, lung, placenta & small intestine

More general terms

• solute carrier family 48 (SLC48, SLC48A)

Database

• OMIM: https://mirror.omim.org/entry/612187
• UniProt: http://www.uniprot.org/uniprot/Q6P1K1.html