chromosomal translocation t4p16.3:14q32.3 (multiple myeloma, FGFR3)
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Introduction
- chromosomal translocation t(4;14)(p16.3;q32.3) involving FGFR3 with the IgH locus may be a cause of multiple myeloma
- increased expression & activating mutations in FGFR3
More general terms
Additional terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/O96028.html
- ↑ Chesi M et al. Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3. Nature Genetics 16:260-4, 1997 PMID: https://www.ncbi.nlm.nih.gov/pubmed/9207791