RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 2; RNA polymerase II subunit A C-terminal domain phosphatase SSU72L2; CTD phosphatase SSU72L2 (SSU72L2, SSU72P2)
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Function
- protein phosphatase
- catalyzes dephosphorylation of the C-terminal domain of RNA polymerase II
- plays a role in RNA processing & termination
H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate
H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +phosphate
Structure
belongs to the SSU72 phosphatase family,