histone H2A.J; H2a/j (H2AFJ)

Function

• monoubiquitination of Lys-120 gives a specific tag for epigenetic transcriptional repression (putative)
• phosphorylation on Ser-2 is enhanced during mitosis & directly represses transcription

Structure

belongs to the histone H2A family

Compartment

nucleus (putative)

Alternative splicing

named isoforms=2

More general terms

• histone-H2A
• phosphoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5576
• UniProt: http://www.uniprot.org/uniprot/Q9BTM1.html