thymosin beta-15A; NB thymosin beta; thymosin-like protein 8 (TMSB15A, TMSL8, TMSNB)

Function

• plays a role in organization of the cytoskeleton
• binds to & sequesters actin monomers (G actin) & thus inhibits actin polymerization (putative)

Structure

belongs to the thymosin beta family

Compartment

cytoplasm, cytoskeleton (putative)

Expression

• neuroblastoma-specific
• down-regulated by TGFB1

More general terms

• thymosin-beta

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=11013
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=286527
• OMIM: https://mirror.omim.org/entry/601587
• UniProt: http://www.uniprot.org/uniprot/P0CG34.html