regulator type Rh-null hemolytic anemia (Rh-deficiency syndrome)

Pathology

• erythrocytes
  • altered ion transport system
  • abnormal membrane phospholipid organization

Genetics

• associated with defects in RHAG

Clinical manifestations

• chronic hemolytic anemia

Laboratory

• complete blood count (CBC)
• peripheral blood smear:
  • erythrocytes have a stomatocytosis & spherocytosis morphology
• increased erythrocyte osmotic fragility

More general terms

• hemolytic anemia

Database

• OMIM: https://mirror.omim.org/entry/268150