clodronate; clodronic acid (Clodronsaeure, Clasteon, Bonefos, Loron)
Jump to navigation
Jump to search
Introduction
1st generation bisphosphonate not available in USA.
Indications
- adjunctive to androgen-deprivation therapy in men with metastatic prostate cancer
Dosage
More general terms
References
- ↑ Dearnaley DP et al Adjuvant therapy with oral sodium clodronate in locally advanced and metastatic prostate cancer: Long-term overall survival results from the MRC PR04 and PR05 randomised controlled trials. Lancet Oncol 2009 Sep; 10:872 http://dx.doi.org/10.1016/S1470-2045(09)70201-3
- ↑ Dearnaley DP et al A Double-Blind, Placebo-Controlled, Randomized Trial of Oral Sodium Clodronate for Metastatic Prostate Cancer (MRC PR05 Trial) Journal of the National Cancer Institute 2003 95(17):1300-1311 doi:10.1093/jnci/djg038 http://dx.doi.org/10.1136/bmj.b2477
- ↑ Mason MD et al Oral sodium clodronate for nonmetastatic prostate cancer - Results of a randomized double-blind placebo-controlled trial: Medical Research Council PR04 (ISRCTN61384873). J Natl Cancer Inst 2007 May 16; 99:765-76. PMID: https://www.ncbi.nlm.nih.gov/pubmed/17505072
Database
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=25419
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=31195
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=23724874
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=4444912
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=6331715
- PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=4668904