agammaglobulinemia

Pathology

• immunodeficiency disorder
• developmental defects in maturation of B-cells

Genetics

• see Bruton-type agammaglobulinemia
• chromosomal translocation t(9;20)(q33.2;q12) involving LRRC8 is a cause of non-Bruton type agammaglobulinemia

More general terms

• hypogammaglobulinemia; immunoglobulin deficiency

More specific terms

• agammaglobulinemia type 2
• Bruton type agammaglobulinemia
• X-linked agammaglobulinemia

Database

• OMIM: https://mirror.omim.org/entry/601495