Mycoplasma genitalium
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Epidemiology
- emerging STD
- 21% of young women in on study[2]
- infection (vs colonization) persists for > 12 months
- incidence higher in black women[2]
- no evidence supporting nonsexual routes of transmission in the medical literature[5]
Clinical manifestations
- urethritis & cervicitis like chlamydia
Laboratory
- Mycoplasma genitalium DNA
- nucleic acid amplification tests are the only reliable method of diagnosis
- may not be widely available
Management
- continue to follow the CDC recommendations for urethritis but .. doxycycline is not reliable, azithromycin once ?
- azithromycin for 5 days (Z-Pak) 500 mg day 1, then 250 mg QD
- oxifloxacin (Avelox) 400 mg daily for 10 days is sometimes effective
More general terms
References
- ↑ Prescriber's Letter 14(8): 2007 Mycoplasma genitalium: An Emerging Sexually Transmitted Disease Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=230802&pb=PRL (subscription needed) http://www.prescribersletter.com
- ↑ 2.0 2.1 2.2 Sena AC, Lee JY, Schwebke J et al. A silent epidemic: The prevalence, incidence and persistence of Mycoplasma genitalium among young, asymptomatic high-risk women in the United States. Clin Infect Dis 2018 Jun 18; 67:73-79. PMID: https://pubmed.ncbi.nlm.nih.gov/29342269 https://academic.oup.com/cid/article-abstract/67/1/73/4802235
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 20 American College of Physicians, Philadelphia 2025
- ↑ Wikipedia: Mycoplasma genitalium https://en.wikipedia.org/wiki/Mycoplasma_genitalium
- ↑ 5.0 5.1 Hjorth SV, Bjornelius E, Lidbrink P et al Sequence-based typing of Mycoplasma genitalium reveals sexual transmission. J Clin Microbiol. 2006 Jun;44(6):2078-83. PMID: https://pubmed.ncbi.nlm.nih.gov/16757601 PMCID: PMC1489459 Free PMC article.