JC virus
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Introduction
Supercoiled virus.
The virus is so named (JC virus) because it was isolated from the post mortem brain of a patient John Cunningham (JC), with PML.
Epidemiology
-JC virus is an opportunistic infection. Infection is common; antibodies to JC virus are present in 80% of adults.
Pathology
- etiologic agent of progressive multifocal leukoencephalopathy (PML)
- JC virus causes tumors in hamsters.
- JC virus contains large T-antigen & 4 other genes
Laboratory
More general terms
Additional terms
References
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 11, 18. American College of Physicians, Philadelphia 1998, 2018.
- ↑ Greenfield's Neuropathology, 5th ed., 1992 p. 336, 367-70
- ↑ 3.0 3.1 ARUP Consult: JC Virus - PML The Physician's Guide to Laboratory Test Selection & Interpretation https://www.arupconsult.com/content/jc-virus