actin, cytoplasmic 2; gamma-actin (ACTG1, ACTG)

Function

• cytoplasmic actins
• role in cell motility
• polymerization of globular actin (G-actin) leads to a structural filament (F-actin)
• each actin can bind to 4 others

Structure

belongs to the actin family

Compartment

cytoplasm, cytoskeleton

Pathology

• defects in ACTG1 are the cause of deafness autosomal dominant type 20

More general terms

• actin
• phosphoprotein

More specific terms

• G-actin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=71
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:71; -.
• OMIM: https://mirror.omim.org/entry/102560
• OMIM: https://mirror.omim.org/entry/604717
• UniProt: http://www.uniprot.org/uniprot/P63261.html