sulfatide; galactocerebroside sulfate

Function

• role in myelin function & stability

Expression

• primarily in the oligodendrocytes in the central nervous system

Pathology

• metachromatic leukodystrophy is a lysosomal storage disease characterized by accumulation of sulfatides due to an inability to degrade them in lysosomes

alterations in sulfatide metabolism may occureearly in the course of Alzheimer's disease

More general terms

• galactocerebroside (galactosylceramide)
• sulfate (SO4=)

Additional terms

• arylsulfatase-A (cerebroside sulfatase, [contains: arylsulfatase A component B; arylsulfatase A component C], ARSA)