neuroprotectin D1 (NPD1)

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Introduction

Neuroprotective agent formed via lipoxygenase-mediated metabolism of docosahexaenoic acid.

More general terms

Additional terms

References

  1. Lukiw WJ, Cui JG, Marcheselli VL, Bodker M, Botkjaer A, Gotlinger K, Serhan CN, Bazan NG. A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. J Clin Invest. 2005 Oct;115(10):2774-83. PMID: https://www.ncbi.nlm.nih.gov/pubmed/16151530
  2. Bazan NG. Neuroprotectin D1 (NPD1): a DHA-derived mediator that protects brain and retina against cell injury-induced oxidative stress. Brain Pathol. 2005 Apr;15(2):159-66. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15912889
  3. Mukherjee PK, Marcheselli VL, Serhan CN, Bazan NG. Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress. Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8491-6. Epub 2004 May 19. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15152078