normeperidine (Norpethidine)

Introduction

Metabolite of meperidine.

Pharmacokinetics

• 1/2life 14-21 hours
• excreted in the urine
• 1/2life increases to 35 hours with renal insufficiency

elimination via kidney

1/2life = 14-21 hours

Adverse effects

• myoclonus & seizures

• drug adverse effects of opiates
• drug adverse effects of psychotropic agents
• drug adverse effects of sedatives

Laboratory

• normeperidine in specimen
  • normeperidine in gastric fluid
  • normeperidine in saliva
  • normeperidine in serum/plasma/blood
    • normeperidine in serum/plasma
  • normeperidine in urine

More general terms

• piperidine
• opiate
• opioid receptor agonist (narcotic)
• pharmacologic metabolite

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=32414
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=32413