esomeprazole (Nexium)

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Introduction

Tradename: Nexium. Generic approved Jan 2015[3]

S-isomer of omeprazole (racemic mixture of S & R isomers).

Dosage

  • 20-40 mg QD 1 hour before meals

Capsules: 20 & 40 mg (OK to open capsule & mix with a small amount of applesauce)

Nexium IV for intravenous infusion

Pharmacokinetics

elimination via liver

1/2life = 0.5-1.5 hours

protein binding = 95 %

Adverse effects

More general terms

Component of

References

  1. Prescriber's Letter 8(1):1 2001
  2. Prescriber's Letter 8(3):13 2001
  3. 3.0 3.1 Brooks M FDA Clears First Generic Esomeprazole for GERD. Medscape. Jan 26, 2015 http://www.medscape.com/viewarticle/838739
    FDA News Release. January 26, 2015 FDA approves first generic esomeprazole. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm431648.htm

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