colesevelam (Welchol)
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Introduction
Tradname: Welchol
Pregnancy category: apparently safe during pregnancy[2]
Dosage
Tabs: 625 mg
Adverse effects
- better tolerated than older bile acid resins
- less likely to cause constipation
- constipation, heartburn, nausea, eructation, bloating
Drug interactions
- less likely interfere with absorption of other drugs than older bile acid resins
Mechanism of action
- bile acid sequestrant
- lowers LDL-cholesterol by 19%
- lowers plasma glucose by unknown mechanism[2]
Notes
Also see cholestyramine.
Cost: $164/30 days (2005)