doublecortin domain

Introduction

N-terminal domain consisting of 1 or 2 tandemly repeated copies of about 80 amino acid residues, probably binding tubulin & enhancing microtubule polymerization.

Proteins known to contain a DC domain:

• doublecortin
• serine/threonine protein kinase DCAMKL1
• retinitis pigmentosa 1 protein

More general terms

• peptide motif
• domain

Additional terms

• neuronal migration protein doublecortin; lissencephalin-X; Lis-X; doublin (DCX, DBCN, LISX)