pim-1 proto-oncogene

From Aaushi
Jump to navigation Jump to search

Introduction

pim-1 may be constitutively transcribed & regulated by trans- criptional attenuation via premature transcriptional termination.

Notes

There is a pim1 gene in Saccharomyces pombe that is a homolog of RCC1. The product of the yeast gene is a serine/threonine kinase implicated in coupling S -> M phase transition in the cell cycle.

More general terms

References

  1. OMIM https://mirror.omim.org/entry/164960
  2. Nagarajan & Narayana Biochem Biophys Res Comm 190:435 1993
  3. Reeves et al Gene 90:303 1990
  4. Mizuno et al. Biochemical & Biophysical Research Communications 281:663-669, 2001

Database