ROCK1 (rho-associated coiled-coil-containing protein kinase) gene
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Introduction
A segmental duplication of chromosome 18 involving ROCK1 & USP14 is one of the few features distinguishing the human genome from the chimpanzee genome.[1][2]
More general terms
References
- ↑ 1.0 1.1 Fortna A, Kim Y, MacLaren E, Marshall K, Hahn G, Meltesen L, Brenton M, Hink R, Burgers S, Hernandez-Boussard T, Karimpour- Fard A, Glueck D, McGavran L, Berry R, Pollack J, Sikela JM. Lineage-specific gene duplication and loss in human and great ape evolution. PLoS Biol. 2004 Jul;2(7):E207. Epub 2004 Jul 13. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15252450
- ↑ 2.0 2.1 Goidts V, Szamalek JM, Hameister H, Kehrer-Sawatzki H. Segmental duplication associated with the human-specific inversion of chromosome 18: a further example of the impact of segmental duplications on karyotype and genome evolution in primates. Hum Genet. 2004 Jul;115(2):116-22. Epub 2004 May 7. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15133654