ARHGEF5 (rho guanine nucleotide exchange factor 5) gene (transforming immortalized mammary oncogene, TIM)

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Introduction

A segmental duplication of chromosome 7 involving ARHGEF5 is one of the few features distinguishing the human genome from the chimpanzee genome.[1]

More general terms

References

  1. 1.0 1.1 Fortna A, Kim Y, MacLaren E, Marshall K, Hahn G, Meltesen L, Brenton M, Hink R, Burgers S, Hernandez-Boussard T, Karimpour- Fard A, Glueck D, McGavran L, Berry R, Pollack J, Sikela JM. Lineage-specific gene duplication and loss in human and great ape evolution. PLoS Biol. 2004 Jul;2(7):E207. Epub 2004 Jul 13. PMID: https://www.ncbi.nlm.nih.gov/pubmed/15252450

Database