FMR-1 gene
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Introduction
Xq27.3
Structure
- contains trinucleotide repeat (CGG) in 5' untranslated region
Pathology
- gene for Fragile X syndrome
- contains trinucleotide repeat (CGG) in 5' untranslated region
- unaffected family members have <50 repeats
- affected family members may have expansions of thousands of base pairs
More general terms
Additional terms
References
- ↑ Ross CA, McInnis MG, Margolis RL, Li SH. Genes with triplet repeats: candidate mediators of neuropsychiatric disorders. Trends Neurosci. 1993 Jul;16(7):254-60. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7689767