Stanniocalcin-1; STC-1 (STC1 STC)

Function

• stimulates renal phosphate reabsorption in fish & rats
• prevents hypercalcemia in fish

Structure

belongs to the stanniocalcin family

Compartment

secreted

Expression

• expressed in most tissues
• highest levels in ovary, prostate, heart, kidney & thyroid
• in the kidney, expression is confined to the nephron, specifically in the distal convoluted tubule & in the collecting tubule
• not detected in the brain, liver, spleen, peripheral blood leukocytes & adrenal medulla

More general terms

• hormone
• glycoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6781
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6781
• OMIM: https://mirror.omim.org/entry/601185
• UniProt: http://www.uniprot.org/uniprot/P52823.html