ribonucleoprotein-2 motif

^[1]^[2]

Introduction

Inside the ribonucleoprotein [[[A18364|RNP]]] motif there are 2 regions which are highly conserved. The 1st is a hydrophobic segment of 6 residues (RNP-2 motif), the 2nd is an octapeptide motif (RNP-1 motif).

↑ Zamore PD, Zapp ML, Green MR. Gene expression. RNA binding: beta s and basics. Nature. 1990 Dec 6;348(6301):485-6. No abstract available. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1701031
↑ Nagai K, Oubridge C, Jessen TH, Li J, Evans PR. Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A. Nature. 1990 Dec 6;348(6301):515-20. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2147232