calcipressin-3; Down syndrome candidate region 1-like protein 2; myocyte-enriched calcineurin-interacting protein 3; MCIP3; regulator of calcineurin 3 (RCAN3, DSCR1L2)

Function

• inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A
• could play a role during central nervous system development

Structure

belongs to the RCAN family

Alternative splicing

named isoforms=2

Expression

• highest expression in heart, skeletal muscle kidney, liver & peripheral blood leukocytes
• lower expression in all other tissues

More general terms

• calcipressin
• phosphoprotein

Additional terms

• calcineurin; serine/threonine protein phosphatase 3 (formerly PP2B)
• Down's syndrome
• myocyte
• thyroid hormone

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=11123
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:11123
• OMIM: https://mirror.omim.org/entry/605860
• UniProt: http://www.uniprot.org/uniprot/Q9UKA8.html