dynein light chain 2B (dynein light chain roadblock-type 2, DYNLRB2, DNCL2B, DNLC2B)

Function

• dynein light chain
• may be involved in assembly & motor function of dynein

Structure

belongs to the GAMAD family

Compartment

cytoplasm

Expression

• expressed in heart, brain, placenta, skeletal muscle, prostate & small intestine > kidney, pancreas, spleen, testis, ovary & colon > lung, liver, thymus & leukocyte

Pathology

• expression is significantly down-regulated in hepatocellular carcinoma

More general terms

• dynein light chain
• protease inhibitor

Additional terms

• dynein

Database

• OMIM: https://mirror.omim.org/entry/607168
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8365
• UniProt: http://www.uniprot.org/uniprot/Q8TF09.html