neurotrophin-4; NT-4; neurotrophin-5; NT-5; neutrophic factor 4 (NTF4, NTF5)

From Aaushi

Jump to navigation Jump to search

^[1]^[2]^[3]

Function

target-derived survival factor for peripheral sensory sympathetic neurons

Structure

belongs to the NGF-beta family

Compartment

Expression

highest levels in prostate, lower levels in thymus, placenta, & skeletal muscle
expressed in embryonic & adult tissues

Pathology

defects in NTF4 may be associated with susceptibility to primary open angle glaucoma type 1O

More general terms

References

↑ UniProt http://www.uniprot.org/uniprot/P34130.html
↑ Hallbook F et al. Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary. Neuron 6:845-858 1991 PMID: https://www.ncbi.nlm.nih.gov/pubmed/2025430
↑ Berkemeier LR et al. Neurotrophin-5: a novel neurotrophic factor that activates trk and trkB. Neuron 7:857-66 1991 PMID: https://www.ncbi.nlm.nih.gov/pubmed/1742028

Database

Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4909
Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4909
OMIM: https://mirror.omim.org/entry/162662
OMIM: https://mirror.omim.org/entry/613100
UniProt: http://www.uniprot.org/uniprot/P34130.html

Retrieved from "https://aaushi.info/w/index.php?title=A145415&oldid=1062627"

↑ Back to top